New Orleans Passenger lists record the Syme's travel from Scotland, arriving in New Orleans, via the ship North Atlantic on 1 November 1850. They then head to Missouri (where brother George is born) but are in Illinois by 1855 (where sister Jennette us born) 1860 census records show they are still living in Illinois. 1870 census records show the entire family living in Utah by 1870. There are records placing, at the least, Barbara in Utah by 1861 because brother Richard was born in Utah in December of that year. Further research is needed to determine whether the family came out together or separately.
Census records have their last name recorded as "Simms".