The French Mission was organized 18 June 1850. It was closed in 1864, though missionary work did continue under the direction of the other missions in Europe. On 15 October 1912 the mission was reorganized, but it was closed two years later, on 18 September 1914, due to the outbreak of World War I. A few years after the war, the French Mission was reorganized from the Swiss-German Mission and the Netherlands Mission in December 1923. It remained open until World War II, closing on 14 December 1939 due to the war. On 23 April 1946 the mission reopened once again.
Publication of Étoile du Déséret began in May 1851 and ran until April 1852. Le Réflecteur began in 1853, but ceased by the end of the year. The French translation of the Book of Mormon, overseen and completed by officers of the French Mission, came off the press in January 1852.
When the mission was reorganized in 1912 it encompassed France and the French-speaking inhabitants of Switzerland, Belgium, and Italy. This boundary included the branches of Lausanne, Lyons, La Chaux-de-Fonds, Paris, Neuchatel, Geneva, Liege, Seraing, Verviers, Brussles, and Lille.
During a meeting at Lausanne held 20 August 1923, it was decided to unify the French-speaking areas of the Swiss-German and Netherlands Missions into one mission. When the French Mission was reorganized on 1 December 1923 it encompassed France, Belgium, and the French-speaking part of Switzerland.
The mission home was located at 12 Avenue de la Gare des eaux-Vives, Geneva, Switzerland.
In 1931, the mission home moved to Rue Saint Cloud, 40 bis Ville d'Avray, France. It moved again in 1934 to 37 Ave., du General Serrail, Paris, France. In 1936 it was relocated to 65 Rue de Campine, Leige, Belgium.
The mission was closed on 14 December 1939 due to World War II.